![]() No fetal malformations were observed in rats and rabbits at doses approximately 2 (rats) and 10 (rabbits) times a human dose of 100 mg/day. Additionally, increases in the number of umbilical hernias, irregularly shaped bones, and delays in fetal skeletal maturation were observed in the study at doses 15 times the human dose of 100 mg/day. Reduced fetal weights were observed in rabbits given this drug during the period of organogenesis at doses equivalent to 5 times the human dose of 100 mg/day. Reduced nursing behavior and decreased body weights were observed at 2 times the human dose. Rats administered this drug during gestation and lactation showed increases in stillborn pups and decreases in pup survival at doses equivalent to the human dose of 100 mg/day. ![]() Long-acting opioids should not be used during and immediately prior to labor, when short acting analgesics or other analgesic techniques are more appropriate. Women should be advised of the risk of neonatal abstinence syndrome and ensure that appropriate treatment will be available. Risk Summary: Based on animal data, may cause fetal harm prolonged maternal use of opioids during pregnancy may cause neonatal opioid withdrawal syndrome. ![]() Do not stop using any medication without first talking to your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not use more than the recommended dose of HYDROcodone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Likewise, you should avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of hydrocodone. If you are taking certain long-acting formulations of hydrocodone, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. Do not stop using any medications without first talking to your doctor.ĭo not use alcohol or medications that contain alcohol while you are receiving treatment with HYDROcodone. Avoid driving or operating hazardous machinery until you know how the medications affect you. You should avoid or limit the use of alcohol while being treated with these medications. Some people may also experience some impairment in thinking and judgment. In addition, combining these medications may increase side effects such as dizziness, drowsiness, and difficulty concentrating. You should contact your doctor immediately if you experience these symptoms during treatment. ![]() Severe cases may result in coma and even death. Using HYDROcodone together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. The following applies to the ingredients:
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |